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Cardiovascular Business Week

Susan Hasty, Publisher

Table of Contents . . . June 22nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Business Week | Other Publications

Evalve, Inc. - Device firm announces completion of a $35M series C financing

GI Dynamics, Inc. - Device company focused on obesity secures $12M

Medtronic, Inc. - Medical device company announces fourth quarter results

SynCardia Systems, Inc. - $3.7M Series B financing to advance development of total artificial heart

Abbott Laboratories - StarClose vascular closure system launched

Abbott Laboratories - Zemplar (Paricalcitol Injection) receives FDA approval for pediatric use

Aberdeen Children's Hospital - Reduced airway function in infancy associated with persistent wheeze at age 11

Abiomed, Inc. - AbioCor replacement heart implanted in 14th patient

Alteon, Inc. - Alagebrium demonstrates benefits on heart, kidney in preclinical studies

American Heart Association - Air pollution is serious cardiovascular risk

Artificial Heart - Man-made heart provides woman new lease on life

Baylor Univ. Medical Center - B-type natriuretic peptide levels are associated with mitral regurgitation

Belarussian State University - Ultrasound affects structure and function of proteins of PPSB complex

Biophan Technologies, Inc. - Details of pacemaker study indicate efficacy of biomedical technology

Boston Scientific Corporation - Enrollment in Taxus registry completed

Boston University - Impaired apoptotic cell clearance enhances atherogenesis and autoimmune disease

Boston VA Medical Center - Erectile dysfunction may portend cardiovascular problems

Business Update - Detroit Medical Center hires five new heart doctors to boost cardiology program

CardioTech International, Inc. - Heparin coating protects blood during open-heart procedures

Catholic University of the Sacred Heart, Largo Gem - Leptin modulates inflammation in relapsed patients

Charles University, Czech Republic - Thrombocyte activity is marker of LDL-apheresis intensity

Cheltenham General Hospital - Surgery best option for preventing recurrence of venous leg ulcers

CHU Vaudois - Lupus-like syndrome linked to simvastin therapy

Conor Medsystems, Inc. - Positive results presented from PISCES stent trial

Cordis Corporation - Diabetic patients benefit from Cypher Sirolimus-eluting coronary stent

Cordis Corporation - New clinical data on stent performance announced

Cremona Hospital - Vitamin E in dialysis fluid may reduce endothelial damage

CryoCath Technologies, Inc. - Enrollment completed in first stage of atrial fibrillation study

Daxor Corporation - Data published on study of blood volume measurement

Defibtech - First international shipment made of automated external defibrillators

Donga University, Pusan - Uric acid levels may be linked to cardiovascular risk factors in old Korean men

Duke University Medical Center - Intraoperative metoprolol does not improve beta-adrenergic receptor function

Dyax Corp. - DX-88 placed on clinical hold pending review

Endocardial Solutions, Inc. - Cardiac-related software development and license agreement signed

eResearchTechnology, Inc. - $1.2M study awarded for cardiac safety monitoring

ev3 Inc. - CE Mark approval issued for Protege GPS Nitinol Self-Expanding Stent

Gamida-Cell Ltd. - Preclinical studies show that stem cells may reverse diabetes in mice

Genaera Corporation - New studies focus on overproduction of mucus

Guidant Corporation - E.U. approves two heart disease treatments

Guidant Corporation - Technology company invests in catheter-based technology for heart valve repair

Hanyang University, Seoul - Metabolic syndrome positively associated with cardiovascular disease

Harvard University - Cigarette smoking predicts reduced maximal FEV1 level in males but not females

Healthcare Costs - Hospitals save $22M through supply chain improvement collaborative project

Heart Attack - The Methodist DeBakey Heart Center receives chest pain center accreditation

Heart Center, Siegburg - ABT-578-eluting stents may inhibit restenosis

Heartlab, Inc. - Cardiology imaging and information company to manage stent trial

Henry Ford Hospital, Detroit - Activated neural stem cells contribute to stroke-induced neurogenesis

Huddinge University Hospital - Anti-Gal IgG potentiates NK cell migration via endothelial cell activation

IMPAX Laboratories, Inc. - Generic versions of two drugs receive FDA approval

Inotek Pharmaceuticals Corporation - Potential treatment for aortic aneurysm repair surgery given FDA fast track status

International Obesity Task Force - Data demonstrate cardiovascular impact of weight loss with sibutramine

Istituto Superiore di Sanita, Rome - Cholesterol regulates GCase activity/stability in Niemann-Pick disease type C

Johnson & Johnson - New cardiac syndrome identified

Kaiser Permanente - Mammograms may help predict cardiovascular disease?

Keio University - PAF responsiveness in subjects with plasma PAF acetylhydrolase deficiency

King Pharmaceuticals - Tennessee pharmaceuticals company expands into New Jersey

Kobe University - Carvedilol may reverse MDR1/P-glycoprotein-mediated multidrug resistance

Kumamoto University - Calcium antagonists are effective after acute MI in Japanese subjects

Kurume University - Aortic Starr-Edwards ball valve prosthesis replaced after 28 years

Laval University - Lipoprotein profiles under varied androgen blockade conditions reported

Legal Issues - Man sues Atkins Diet over heart problems

Mahidol University - Mechanism of cardioprotection studied in ovariectomized rats

Mayo Clinic - Daily dip in blood vessel expansion may help explain morning heart attack peak

Medical Discoveries, Inc. - Patent application filed for potential cystic fibrosis treatment

Medical Education - Tennessee health center losing anesthesiology program

Medical University of Lublin - Features of leptin-induced hypertension described

Medtech Insight - New report shows diagnostics driving cardiovascular market

Medtronic, Inc. - 30-day safety data available for coronary stent

Medtronic, Inc. - Intrinsic implantable cardioverter-defibrillator now available in Europe

Medtronic, Inc. - Medtronic launches InSync cardiac resynchronization therapy system in Japan

Mergers & Acquisitions - Medtronic, Genzyme form joint venture for heart-related cell therapy

Methodist Hospital, Houston - Losing even a few pounds may help the obese

Myogen, Inc. - Ambrisentan phase II results presented at ATS 2004

Newcastle University - Researchers discover gene that causes rare disorder

Nicotine Addiction - List linking smoking to diseases expands

Nonobac Life Sciences - Recreation of published results may confirm nanobacteria in arteries and valves

Ochsner Clinic, New Orleans - Angiotensin II provides cerebroprotection against stroke

Orbus Medical Technologies - HEALING II CE mark clinical trial initiated

Ottawa Heart Institute - Mechanical support pumps can be a bridge to cardiac transplantation

Pharmacyclics, Inc. - Vulnerable atherosclerotic plaque identified with novel texaphyrin compounds

Polymedco, Inc. - Homocysteine added to Poly-Chem analyzer testing menu

Procter & Gamble Pharmaceuticals - Moderate hepatic impairment has limited effect on azimilide pharmacokinetics

Puerta Hierro Clinic, Madrid - B-type natriuretic peptide is useful in diagnosing heart failure

Roche Diagnostics - FDA clears new intended uses for Troponin T test

San Martino University Hospital, Genoa - Cord blood stem cells plus fibrin platelet glue used for wound repair

Somanetics Corporation - Cerebral oximetry associated with lower stroke rate after cardiac surgery

SonoSite - Cardiovascular software company acquired

St. Jude Medical, Inc. - Housecall Plus remote monitoring system launched

Stanford University Medical Center - Isoflavone metabolite inhibits ERK-1 activity in vascular smooth muscle cells

Sungkyunkwan University - Study finds molecular variant of ACE associated with hypertension in pregnancy

Thoratec Corporation - Illinois man is 10th in U.S. to survive for year or more with heart pump

Toshiba America Medical Systems Inc. - FDA issues marketing clearance for cardiac flat-panel detector

Tottori University - Mouse model of Down syndrome has congenital heart disease

U.S. Food & Drug Administration - Study of decellularized carotid artery vascular grafts released

Univ. of London Imperial College - Researchers say effects of OCs, HRT on lipoproteins need further investigation

University of California San Francisco - Flavonoid-rich dark chocolate boosts blood vessel function, study suggests

University College London - Heart enlargement is a common cause of sudden death in young people

University College of London - Factor V Leiden associated with increased risk of obstetric complications

University College, London - Socioeconomic status may be linked to heart disease

University Hospital, Louvain - TIPS stent-grafts do not prevent liver transplantation

University of Alabama - Dyspnea at rest may predict heart failure in older adults

University of Alberta - Blood pressure drugs cut death rate in half

University of Alberta - Nitric oxide and GABA mediate adrenomedullin's hypotensive effects in brain

University of Birmingham - Carbonic anhydrase IX predictive of outcome in bladder cancer

University of Edinburgh - Study seeks to improve quality of life for heart failure patients

University of Estadual Campinas - Angiotensin II receptors modulate murine macrophage activity and phagocytosis

University of Frankfurt Clinic - Researchers make dietary recommendations for lipid disorders

University of Jaen - L-type calcium channel subunit expression clarified in developing heart

University of London - Many patients diagnosed with chronic illness stop taking medicines

University of Naples - Lipophilic compounds in tomatoes protect against cardiovascular disease

University of North Carolina - Economic growth is boosting women's obesity in poorer nations

University of Sao Paulo - CTLA-4 blockage increases resistance to infection with Trypanosoma cruzi

University of Southern California - Endovascular management effective for iliac vein occlusive disease

University of Texas, Health Science Center - Heat-inactivated C. pneumoniae is not atherogenic

University of Wisconsin, Madison - Nonviral, intravascular approach to muscular dystrophy gene therapy moves ahead

VA Connecticut Health Care Systems - PAD patients should be aggressively treated for atherosclerotic risk factors

Vasamed - Technology development company names new vice president, sales and marketing

Wakayama Medical University - Leptin and membrane fluidity of erythrocytes in hypertension studied

Wake Forest University - Anemia adversely affects outcome of diastolic heart failure patients

West Nile Virus - Experts say severe West Nile can cause long-term harm damage

Xtent, Inc. - Coating and drug-eluting technology licensed for coronary stent system

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