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Cardiovascular Business Week

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Duke University



New scheme for identifying alpha1A -adrenoceptor splice variants is proposed



December 7th, 2004

A recent report provided an update on human alpha1 -adrenoceptor subtype signaling and genomic organization.

According to the report from the United States, "Alpha1 -adrenoceptors are G-protein-coupled receptors that bind catecholamines. Sixteen distinct human alpha1A -adrenoceptor isoforms have been identified from human tissues, including five full-length and 11 truncated versions. An updated scheme for the identification of alpha1A -adrenoceptor splice variants is proposed."

K.A. Hawrylyshyn and colleagues of Duke University wrote, "Given the established roles of alpha1 -adrenoceptors in...


Source: Cardiovascular Business Week (2004-12-07)

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