Cardiovascular Business Week
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diaDexus, Inc.
Enzyme, inflammation have role in formation of vulnerable plaque, study shows
December 7th, 2004
diaDexus announced findings from a new study that indicate a biological role for Lp-PLA2 (lipoprotein-associated phospholipase A2) in the formation of vulnerable plaque. The data were presented at the American Heart Association (AHA) Scientific Sessions held in New Orleans, Louisiana. In the study, specific monoclonal antibodies were used to identify Lp-PLA2 in serial frozen or paraffin-embedded sections of atherosclerotic plaques from sudden coronary death victims. The data demonstrate that Lp-PLA2 localizes with inflammatory cells and is strongly expressed in the core of atheromas often associated with acute coronary events. In the most rupture...
Source: Cardiovascular Business Week (2004-12-07)
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