Cardiovascular Business Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cardiovascular Business Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cleveland Clinic Foundation
Tethering of protein kinase A may be essential for cardiac muscle contraction
December 7th, 2004
A recent review focused on A-kinase anchoring proteins that target protein kinase A in the heart. "There is increasing evidence that subcellular targeting of signaling molecules is an important means of regulating the protein kinase A (PKA) pathway. Subcellular organization of the signaling molecules in the PKA pathway insures that a signal initiated at the receptor level is transferred efficiently to a PKA substrate eliciting some cellular response. This subcellular targeting appears to regulate the function of a highly specialized cell such as the cardiac myocyte," researchers in the United States report. M.L. Ruehr and colleagues of the Cleveland...
Source: Cardiovascular Business Week (2004-12-07)
|
