Cardiovascular Business Week
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East Tennessee State University, Johnson City
CART peptide fragment 55-102 may excite neurons in intermediolateral cell column
April 26th, 2005
Cocaine- and amphetamine-regulated transcript peptide potentiates spinal glutamatergic sympathoexcitation in anesthetized rats. According to published research from the United States, "Cocaine- and amphetamine-regulated transcript (CART) is widely expressed in the rat central nervous system, notably in areas involved in control of autonomic and neuroendocrine functions. The aim of [our] study was to evaluate the effects of CART peptide fragment 55-102, referred to herein as CARTp, by intrathecal injection on blood pressure (BP) and heart rate (HR) before and after intrathecal glutamate in urethane-anesthetized male Sprague-Dawley rats." P. Scruggs...
Source: Cardiovascular Business Week (2005-04-26)
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