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Cardiovascular Business Week

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Academic Medical Center, Amsterdam



Inflammatory response involving leucocytes plays a role in pathogenesis of MI



April 26th, 2005

High-throughput mRNA profiling highlights associations between myocardial infarction and aberrant expression of inflammatory molecules in blood cells.

According to researchers in the Netherlands, "Studies on the role of inflammation in cardiovascular disease focus on surrogate markers like plasma levels of C-reactive protein or interleukins that are affected by several factors. In [our] study we employ an approach in which the inflammatory mRNA profile of leucocytes is measured directly in a multigene system."

S.B. Wettinger and colleagues of the Academic Medical Center in Amsterdam explained, "We investigated the mRNA profile for 35 inflammatory...


Source: Cardiovascular Business Week (2005-04-26)

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