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Cardiome Pharma Corp.

Phase IIa study for oral RSD1235 initiated in patients with atrial fibrillation

Published in Cardiovascular Business Week, January 10th, 2006

Cardiome Pharma Corp. (CRME)(COM) announced the initiation of a phase IIa pilot study of oral RSD1235 for the prevention of recurrence of atrial fibrillation.

The double-blind, placebo-controlled, randomized, dose-ranging study will measure the safety and efficacy of oral RSD1235 over 28 days of oral dosing in patients at risk of recurrent atrial fibrillation. It is expected that the majority of patients enrolled will have experienced atrial fibrillation for greater than 30 days and less than 180 days in duration. The study will enroll 180 patients across 75 centers in Canada, U.S. and Europe.

Patients with atrial fibrillation in the first stage of...

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