Helsinki University Central Hospital
Cerebral artery aneurysm wall remodeling involves various growth factors
Published in Cardiovascular Business Week, May 16th, 2006
"Remodeling of the SCAA wall, known to be associated with rupture, might be modified with bioactive endovascular implants or systemic drug therapy targeted at growth factor receptors to prevent rupture. The receptors regulating SCAA wall remodeling are, however, unknown," wrote J. Frosen and colleagues, Helsinki University Central Hospital.
They explained, "Immunostaining for 12 growth factor receptors, and markers for matrix synthesis, proliferation, and inflammatory cell infiltration, were analyzed in 21 unruptured and 35...
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