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Atherosclerosis

Reports summarize atherosclerosis research from Vascular Genetics Inc.

Published in Cardiovascular Business Week, November 14th, 2006

A report, "Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus," is newly published data in Atherosclerosis. According to recent research published in the journal Atherosclerosis, "Lipoprotein associated phospholipase A2 (Lp-PLA2) modulates low-density lipoprotein (LDL) oxidation by hydrolysing oxidised phospholipids present on particle surfaces. We investigated whether Lp-PLA2 activity and PLA2G7 A379V genotype were related to mediators of atherosclerosis in a diabetic study."

"Plasma Lp-PLA2 activity (taken in men only) and A379V genotype were investigated with regards to metabolic syndrome (MS), UKPDS risk score, and oxidised LDL...

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