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Kidney & Cardiovascular Disease

LV dysfunction and LV hypertrophy in end-stage renal disease linked to low triiodothyronine

Published in Cardiovascular Business Week, November 14th, 2006

Low triiodothyronine is associated with left ventricular dysfunction and left ventricular hypertrophy in end-stage renal disease patients.

Researchers working in Italy report, "Low free plasma triiodothyronine (fT3) is associated with inflammation and cardiovascular damage in patients with end-stage renal disease (ESRD). We investigated the relationship between fT3, left ventricular systolic function and left ventricular mass in a group of 234 dialysis patients, and modelled the association between fT3 and cardiomyopathy in statistical analyses including both direct (interleukin-6 and C-reactive protein) and inverse (serum albumin) acute phase inflammation...

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