Diabetes Cell Biology
Study results from Royal North Shore Hospital, Department of Cardiology provide new insights into diabetes cell biology
Published in Cardiovascular Business Week, April 10th, 2007
Investigators publish new data in the report "Alloxan-induced diabetes reduces sarcolemmal Na+-K+ pump function in rabbit ventricular myocytes. The effect of diabetes on sarcolemmal Na(+)-K(+) pump function is important for our understanding of heart disease associated with diabetes and design of its treatment. We induced diabetes characterized by hyperglycemia but no other major metabolic disturbances in rabbits," scientists in Australia report.
"Ventricular myocytes isolated from diabetic rabbits and controls were voltage clamped and internally perfused with the whole cell patch-clamp technique. Electrogenic Na(+)-K(+) pump current (I(p), arising from the 3:2...
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