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Abdominal Aortic Aneurysm

Studies from University of South Florida have provided new information about abdominal aortic aneurysm

Published in Cardiovascular Business Week, August 28th, 2007

Fresh data on abdominal aortic aneurysm are presented in the report "MF-tricyclic inhibits growth of experimental abdominal aortic aneurysms." According to recent research published in the Journal of Surgical Research, "Experimental abdominal aortic aneurysm (AAA) development can be pharmacologically suppressed by inhibiting matrix metalloproteinase-9 (MMP-9). Cyclooxygenase-2 (COX-2) inhibitors are potent anti-inflammatory agents that have been demonstrated to inhibit experimental aneurysm development."

"We hypothesized that treatment with MF-tricyclic, a selective COX-2 inhibitor, incorporated into rodent chow would inhibit aneurysm development in a rat AAA...

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