Chronic Heart Failure

Data on chronic heart failure published by researchers at University of Groningen

Published in Cardiovascular Business Week, February 5th, 2008

"Aims Advanced glycation end-products (AGEs) have been proposed as a novel factor involved in the development and progression of chronic heart failure (CHF). We aimed to determine whether plasma levels of N-epsilon-(carboxymethyl)lysine (CML) and N-epsilon-(carboxyethyl)lysine (CEL), two well-known AGEs, are related to the severity and prognosis of CHF," scientists in Netherlands report.

"Methods and results A total of 102 CHF patients, aged 58 +/- 12 years, with an average left ventricular ejection fraction of 28 +/- 9% were followed for 1.7 (1.2-1.9) years. NYHA functional class and NT-pro-BNP were used as estimates of the severity of CHF. CML and CEL were determined...

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Source: Cardiovascular Business Week (2008-02-05)

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