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Sepsis

New sepsis research from University catholique of Louvain discussed

Published in Cardiovascular Business Week, February 5th, 2008

Researchers detail in 'Sepsis is associated with an upregulation of functional beta3 adrenoceptors in the myocardium,' new data in sepsis. According to recent research from Brussels, Belgium, "To analyze the implication of the beta3-adrenoceptor (beta3-AR) pathway in human septic myocardium and a murine model of sepsis, a condition associated with myocardial depression. beta3-AR and eNOS protein abundance were increased (332±66.4% and 218±39.3; p<0.05) in hearts from septic patients."

"The effect of BRL37344, a beta3-AR-preferential agonist, was analyzed by videomicroscopy on the contractility of neonatal mouse ventricular myocytes (NMVM) incubated with...

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