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Proteomics

Studies from University of Calgary, Department of Pharmacology in the area of proteomics published

Published in Cardiovascular Business Week, February 12th, 2008

New investigation results, 'Proteinase-activated receptor-2 activating peptides: distinct canine coronary artery receptor systems,' are detailed in a study published in American Journal of Physiology - Heart and Circulatory Physiology. "In canine coronary artery preparations, the proteinase-activated receptor-2 (PAR(2)) activating peptides (PAR(2)-APs) SLIGRL-NH(2) and 2-furoyl-LIGRLO-NH(2) caused both an endothelium-dependent relaxation and an endothelium-independent contraction. Relaxation was caused at peptide concentrations 10-fold lower than those causing a contractile response," scientists writing in the American Journal of Physiology - Heart and Circulatory Physiology...

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