Cardiology

Data on cardiology reported by researchers at University of Virginia

Published in Cardiovascular Business Week, February 26th, 2008

"Angiotensin II type 2 receptor (AT(2)R) overexpression (AT(2)TG) attenuates left ventricular remodeling in a mouse model of anterior myocardial infarction (MI). We hypothesized that the beneficial effects of cardiac AT(2)TG are mediated via the bradykinin subtype 2 receptor (B2R)," scientists in the United States report.

"Fourteen transgenic mice overexpressing the AT(2)R (AT(2)TG mice), 10 mice with a B2R deletion (B2KO mice), 13 AT(2)TG mice with B2R deletion (AT(2)TG/B2KO mice), and 11 wild-type (WT) mice were studied. All mice were on a C57BL/6 background. Mice were studied by cardiac magnetic resonance imaging at baseline and days 1, 7, and 28 after MI induced by...

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Source: Cardiovascular Business Week (2008-02-26)

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