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Kidney Disease

Studies by M. Gallieni and co-authors describe new findings in kidney disease

Published in Cardiovascular Business Week, April 22nd, 2008

"Chronic kidney disease (CKD) is associated with an impaired endothelial function, which may contribute to cardiovascular events. Whether impairment in endothelial function is involved in the circulatory response to orthostatic stress is unknown," researchers in Milan, Italy report.

"We assessed endothelial function via brachial artery flow-mediated dilation (BAFMD), an index of endothelial-dependent vasodilation. We measured changes in brachial artery diameter (BAD) and blood flow by Doppler ultrasound in 35 CKD patients on hemodialysis, 37 young healthy controls (HC) and 50 non-uremic matched controls (MC), in the supine position and after 60 head-up tilting (HUT). In...

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