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Angiotensins

Research from R. Dueandersen and co-authors yields new data on angiotensins

Published in Cardiovascular Business Week, May 6th, 2008

" Activity in the renin-angiotensin system (RAS) may influence the susceptibility to cardiac arrhythmia. To study the effect of basal RAS activity on cardiac repolarization during myocardial stress induced by hypoglycaemia or hypoxaemia in healthy humans," scientists writing in the journal Europace report.

"Methods and results Ten subjects with high RAS activity and 10 subjects with low RAS activity were studied on three different occasions: (i) hypoglycaemia (nadir P-glucose 2.7 +/- 0.5 mmol/L), (ii) hypoxaemia (nadir pO(2) 5.8 +/- 0.5 kPa), and (iii) normoglycaemic normoxia (control day). QT parameters were registered by Hotter monitoring. Hypoglycaemia and...

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