Cardiovascular Business Week
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Allograft Rejection
Researchers from University of Maryland discuss findings in allograft rejection
May 13th, 2008
"we have previously demonstrated that a peripheral blood transcriptional profile using 11 distinct genes predicts onset of cardiac allograft rejection weeks to months prior to the actual event. In this analysis, we ascertained the performance of this transcriptional algorithm in a Bayesian representative population: 28 cardiac transplant recipients who progressed to moderate to severe rejection; 53 who progressed to mild rejection; and 46 who remained rejection-free," researchers in the United States report. "Furthermore, we characterized longitudinal alterations in the transcriptional gene expression profile before, during and after recovery from rejection. In this patient...
Source: Cardiovascular Business Week (2008-05-13)
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