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Burnham Institute

Nerve cells derived from stem cells and transplanted into mice may lead to improved brain treatments

Published in Cardiovascular Business Week, July 8th, 2008

LA JOLLA, Calif., June 25, 2008--Scientists at the Burnham Institute for Medical Research have, for the first time, genetically programmed embryonic stem (ES) cells to become nerve cells when transplanted into the brain, according to a study published in The Journal of Neuroscience. The research, an important step toward developing new treatments for stroke, Alzheimer's, Parkinson's and other neurological conditions showed that mice afflicted by stroke showed tangible therapeutic improvement following transplantation of these cells. None of the mice formed tumors, which had been a major setback in prior attempts at stem cell transplantation.

The team was led by Stuart...

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