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Heart Disease

Reports from S. Guthikonda et al highlight recent research in heart disease

Published in Cardiovascular Business Week, September 30th, 2008

"Objectives The aim of this study was to evaluate the relationship between reticulated platelets (RPs), platelet size, and platelet function in patients with stable coronary artery disease (CAD) taking aspirin and clopidogrel. Reticulated platelets are young platelets that are larger and possibly more active than non-RPs," investigators in the United States report.

" Flow cytometry was used to measure RPs after staining with thiazole orange and to define the upper 20% and lower 20% of platelets by size. Platelet aggregation was measured with light transmission aggregometry (LTA); platelet activation was assessed by measuring activated platelet surface expression of...

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