Aetna
Aetna Analysis Supports Data Showing Blood Clot Drug May Be Less Effective When Taken with Commonly Used Acid-Reducer
Published in Cardiovascular Business Week, September 30th, 2008
Clopidogrel, a drug used in treating coronary artery disease and marketed as Plavix(R), may be less effective when it interacts with acid reducing proton pump inhibitors (PPIs) (e.g., Prilosec(R), Nexium(R)) according to an Aetna (NYSE:AET) analysis published in the September 16th issue of the Journal of the American College of Cardiology. Initial results showed (a) a one year acute myocardial infarction (MI) of 5.03 percent in the group taking PPIs often; (b) a 3.08 percent one year acute MI rate in the group taking PPI some of the time; and (c) a one year acute MI rate of 1.38 percent in the group with no PPI use.*
"This is one study, one piece of the data puzzle, but...
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