Ischemia Immunology
Researchers from Massachusetts General Hospital report recent findings in ischemia immunology
Published in Cardiovascular Business Week, October 7th, 2008
Scientists discuss in 'Innate immune adaptor MyD88 mediates neutrophil recruitment and myocardial injury after ischemia-reperfusion in mice' new findings in ischemia. According to a study from the United States, "MyD88 is an adaptor protein critical for innate immune response against microbial infection and in certain noninfectious tissue injury. The present study examined the role of MyD88 in myocardial inflammation and injury after ischemia-reperfusion (I/R)."
"I/R was produced by coronary artery ligation for 30 min followed by reperfusion. The ratios of area at risk to left ventricle (LV) were similar between wild-type (WT) and MyD88-deficient (MyD88-/-) mice....
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