JAMA and Archives Journals

Common COPD medications linked with increased risk of CV death, heart attack

Published in Cardiovascular Business Week, October 7th, 2008

The use of inhaled anticholinergic agents (medications that help reduce bronchospasm) by patients with chronic obstructive pulmonary disease (COPD) is associated with a significantly increased risk of heart attack, stroke of cardiovascular death, according to a meta-analysis of randomized trials published in the September 24 issue of JAMA.

COPD is the fourth leading cause of chronic illness and death in the United States, and is projected to rank fifth in 2020 in burden of disease worldwide. Inhaled anticholinergic agents (including ipratropium bromide or tiotropium bromide) are widely used in patients with COPD, but their effect on the risk of cardiovascular outcomes...

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Source: Cardiovascular Business Week (2008-10-07)

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