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Enzyme Research

Studies in the area of enzyme research reported from University of Dundee

Published in Cardiovascular Business Week, August 4th, 2009

"Fuller W, Howie J, McLatchie LM, Weber RJ, Hastie CJ, Burness K, Pavlovic D, Shattock MJ. FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C. Am J Physiol Cell Physiol 296: C1346-C1355, 2009," researchers in Scotland report.

"First published April 1, 2009; doi:10.1152/ajpcell.00523.2008.-FXYD1 (phospholemman), the primary sarcolemmal kinase substrate in the heart, is a regulator of the cardiac sodium pump. We investigated phosphorylation of FXYD1 peptides by purified kinases using HPLC, mass spectrometry, and Edman sequencing, and FXYD1 phosphorylation in cultured adult rat ventricular myocytes...

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