Anoxia

Research from M.R. Mont and co-researchers in the area of anoxia published

Published in Cardiovascular Business Week, August 4th, 2009

According to recent research from the United States, "Calcium has been proposed as a primary influence on cell death during ischemic episodes in myocardial cells. One component of calcium entry into a cell is resting calcium influx."

"This basal movement of calcium is blocked by 100 mu mol/L gadolinium chloride (GdCl3) in cardiac myocytes. Therefore, GdCl3 should be cardioprotective under anoxic conditions. To test this, cardiac myocytes isolated from adult male rats were subjected to anoxia (100% N-2) in the presence or absence of 100 mu mol/L GdCl3 in one of 2 ways. In the first method, cells were suspended in media and rendered anoxic for 0, 30, and 60 min, after...

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Source: Cardiovascular Business Week (2009-08-04)

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