Enzyme Research

New enzyme research research reported from L. Yang and co-authors

Published in Cardiovascular Business Week, September 22nd, 2009

According to recent research from the United States, "The regulation of Ca2+ influx through the phosphorylation of the L-type Ca2+ channel, Ca(v)1.2, is important for the Modulation of excitation-contraction (E-C) coupling in the heart. Ca(v)1.2 is thought to be the target of multiple kinases that mediate the signals of both the renin-angiotensin and sympathetic nervous systems."

"Detailed biochemical information regarding the protein phosphorylation reactions involved in the regulation of Ca(v)1.2 is limited. The protein kinase C (PKC) Family of kinases can Modulate cardiac contractility ill a complex manner, such that contractility is either enhanced or depressed and...

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Source: Cardiovascular Business Week (2009-09-22)

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