Life Sciences

Studies from G.S. Dimarco and co-authors have provided new information about life sciences

Published in Cardiovascular Business Week, December 8th, 2009

"Endothelial dysfunction contributes to the increased cardiovascular risk that accompanies CKD. We hypothesized that the soluble VEGF receptor 1 (sFlt-1), a VEGF antagonist, plays a role in endothelial dysfunction and decreased angiogenesis in CKD," investigators in Munster, Germany report.

"We enrolled 130 patients with CKD stages 3 to 5 and 56 age- and gender-matched control patients. Plasma sFlt-1 levels were higher in patients with CKD and, after multivariate regression analyses, exclusively associated with renal function and levels of vWF, a marker of endothelial dysfunction. Compared with serum from control patients, both recombinant sFlt-1 and serum from patients...

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Source: Cardiovascular Business Week (2009-12-08)

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