Anemia
New anemia study findings recently were published by researchers at Ortho Biotech
Published in Cardiovascular Business Week, December 8th, 2009
"Hemoglobin (Hgb) variability when treating anemia in pre-dialysis chronic kidney disease (CKD) patients with erythropoietin stimulating agents (ESAs) may be an important safety consideration, as significant Hgb fluctuations over time appear to be associated with worse outcomes, especially cardiovascular-related outcomes. We analyzed Hgb variability in subjects receiving epoetin alfa (EPO) with extended dosing regimens," scientists writing in the journal Dialysis & Transplantation report.
"We conducted a post-hoc analysis to evaluate Hgb variability in 2 trials of EPO in CKD anemia; both examined Hgb response during dosing intervals up to 4 weeks. I examined 4...
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