Published in Cardiovascular Device Liability Week, September 26th, 2004
According to recent research published in the journal Toxicology, "gamma-Aminobutyric acid (GABA) receptor plays an important regulatory role in human and animal blood pressure; however, whether a GABAergic mechanism is involved in endotoxin intoxication-associated hypotension has never been reported. In vivo effect of the GABAalpha receptor antagonist BMI on mean arterial pressure (MAP), heart rate (HR), and serum nitrite levels were investigated in endotoxin (lipopolysaccharide; LPS)-treated...
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