Bulgarian Academy of Sciences
Acute cobalt poisoning in vivo depresses Ca-sensitive K currents
Published in Cardiovascular Device Liability Week, January 2nd, 2005
According to a study from Bulgaria, "The aim of the present study was to determine whether cobalt poisoning induces haem oxidase isoenzyme-1 (HO-1) in coronary artery smooth muscle, or accounts for any changes in coronary smooth muscle cell (SMCs) membrane ionic currents that could result from this type of heavy metal poisoning."
K. Hristov and colleagues of the Bulgarian Academy of Sciences reported, "In SMCs isolated from cobalt-treated guinea-pig coronaries, K+ channel currents...
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