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Cardiovascular Device Liability Week

Susan Hasty, Publisher

Table of Contents . . . November 13th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Device Liability Week | Other Publications

Albany Medical College -  mef2c is not needed for heart formation after looping morphogenesis

General Medical Center, Mie - 4-D CT angiography provides valuable information on aneurysm hemodynamics

Hippokratio Hospital, Athens - A common pathway may link LV diastolic function and aortic stiffness

Medwave, Inc. - Blood pressure monitoring developer wins right to protect intellectual property

Rambam Medical Center, Haifa - ACE isoform shift may contribute to cardiac remodeling in response to hemodynamic overload

Aarhus University Hospital - Plasminogen activator inhibitor type 1 increased in HIV-associated lipodystrophy

Aastrom Biosciences, Inc. - Tissue repair cells used to treat limb ischemia in diabetic patients

ActivBiotics, Inc. - Biopharma company to pursue development of peripheral arterial disease drug

Allegheny General Hospital, Pittsburgh - Distal-flow femoral artery cannula may reduce distal limb ischemia risk

Alliance Medical Corp. - U.S. FDA grants 510(k) clearance for ultrasound catheter

Alton Ochsner Medical Foundation & Ochsner Clinic - Basiliximab may be useful in heart transplantations

Ambroise Pare University Hospital, Boulogne - Automated cardiac output measurement can quantify intracardiac shunt

American Academy of Allergy, Asthma & Immunology - U.S. allergy, immunology academy reports new asthma practice parameter

Angeles Clinic & Research Institute, Santa Monica - Safety profile of raloxifene supported by results of analysis of MORE trial data

Ark Therapeutics Group plc - Development completed for oxLDL diagnostic kit for prediction of heart attack risk

AstraZeneca - Study finds risks of cardiovascular death or nonfatal myocardial infarction reduced with Atacand

Atrial Fibrillation - New Jersey hospital offers minimally invasive fix for irregular heartbeat

ATS Medical, Inc. - Cardiac surgery device maker closes $19M convertible senior note offering

Austin Heart - Device removes plaque prior to revascularization in peripheral artery disease

Avant Immunotherapeutics, Inc. - Enrollment completed in phase IIb study in women undergoing cardiac bypass surgery

AVI BioPharma, Inc. - Data presented on development of nanoparticle delivery of antirestenotic drugs

Axis-Shield plc - New test for beta natriuretic peptide launched

Baylor College of Medicine, Houston - Antioxidant therapy may control protease inhibitor-associated cardiovascular complications

Baylor College of Medicine, Houston - Danon disease is an underrecognized entity in pediatric cardiology

California Pacific Medical Center, San Francisco - EDPR gradient aids evaluation of pulmonary artery pressures, cardiac dysfunction

Cardiovascular Center, Frankfurt - New device uses radiofrequency energy for PFO closure

Case Western Reserve University, Cleveland - Diet high in fat and salt diet prevented hypertrophic response to hypertension

Cedars Sinai Medical Center, Los Angeles - Drug-eluting stents improve outcomes of patients with aging coronary grafts

Chaim Sheba Medical Center, Tel Hashomer - Consider atropine when vasopressin is administered during CPR

Charles Sturt University, Albury - Seven-day administration of cyclosporine A alters erythrocyte redox balance

Charles University, Plzen - Catecholamines, serotonin, acetylcholine and nitric oxide co-exist in aortic glomus cells

Chiba University - Echocardiographic measurement of DSVR provides estimation of artery stenosis severity

Chinese Academy of Medical Sciences, Beijing - GH-releasing peptides improve cardiac function in CHF rats

Chinese Academy of Sciences, Shanghai - Expanded endothelial progenitor cells help restore blood flow in ischemic limbs

Chinese University of Hong Kong - Lung fluid attenuates cardiac impedance measurements

Chinese University of Hong Kong - Practice of using systolic HF treatments for diastolic HF is theoretically sound

Chinese University of Hong Kong - Volumetric changes after an intervention for HF may help predict outcome

Chonnam National University - Statins decrease restenosis in patients with high C-reactive protein levels

CHU Brugmann HEDERF - Hydroxyethyl starch 130/0.4 suitable as alternative to modified fluid gelatin for volume expansion

Claude Bernard University, Lyon - Antihypertensive medicine does more than reduce blood pressure

Cleveland Clinic Foundation - Inflammation may contribute to pathogenesis of antiarrhythmic-resistant atrial fibrillation

Cleveland Clinic Foundation - Three-year trials demonstrate carotid stent durability in preventing stroke

Clinimex - Adult female patients are more flexible than other women

Collaborations - Alere Medical partners with Joslin Diabetes Center to develop diabetes disease management program

Columbia University - Biventricular assist device support induces right ventricular reverse remodeling

Columbia University - PRAs may help to assess immunologic status after pediatric cardiac transplant

Cornell University, New York - Cerebellar fastigial nucleus-mediated neurogenic neuroprotection involves mitochondria

CorSolutions Inc. - Health intelligence company earns full NCQA accreditation for its disease management programs

Dalhousie University, Halifax - Heat shock differentially regulates cell signaling pathways

Diagnostic Systems Laboratories Corp. - Immunoassay maker acquired by Beckman Coulter

Duke University, Durham - Near infrared laser device can measure brain oxygen levels during surgery

Emory University, Atlanta - PCI can be performed safely in cardiac transplant recipients

Endologix, Inc. - First patients treated in Powerlink trial with 34 mm infrarenal cuff

EP MedSystems, Inc. - Cardiac electrophysiology company replaces CEO Reinhard Schmidt; David Jenkins takes the helm

Erasmus University, Rotterdam - Atorvastatin showed a more favorable effect than other statins

eResearchTechnology, Inc. - ECG core laboratory completes XML process under Mortara Certified Partner program

eResearchTechnology, Inc. - ECG services provider reports record-breaking $32 million in Q3 contracts

European Hospital Georges Pompidou, Paris - Palmaz Genesis stent provides good results for renal artery stent placement

Evanston Hospital - New device brings hope to severe heart disease patients

Eyetech Pharmaceuticals, Inc. - Study suggests new treatment more effective for early-stage macular degeneration

Fitness & Wellness - Exercise amount more important than intensity

FoldRx Pharmaceuticals, Inc. - Phase I study begins with Fx-1006a, to stabilize protein misfolding in hereditary amyloid disorders

Fraunhofer Institute of Toxicology and Toxicology Medicine, Hannover - Changes in disease-related genes may account for rhythm disturbance

G.B. Pant Hospital, New Delhi - Balloon mitral valvuloplasty feasible under transthoracic echocardiographic guidance

Gwathmey, Inc. - Judith Gwathmey selected for U.S. National Institutes of Health program

Hadassah University Hospital, Jerusalem - Different effects of preconditioning suggest different protective mechanisms

Harborview Medical Center - Acute lung injury mortality is fourfold higher than that from heart attack

Harvard University - Model designed to evaluate policies that influence population fish consumption

Harvard University - Study found increased daily mortality from increased concentrations of particulate matter

Harvard University Medical School - Caution suggested when using a sauna

Hellenic Breast Surgeons Society, Athens - Lipidemic profile of women treated with adjuvant exemestane therapy not significantly altered

Hokkaido University - Arginine supplementation encourages exercise-induced angiogenesis

Hopital Center Lyon Sud, Pierre Benite - Emphasis must be placed on lipid panel monitoring and more efficacious therapies

Hopital Edouard Herriot, Lyon - Prediction score results in low risk of recurrent thrombosis in women with increased risk

Hospital 12 de Octubre, Madrid - Article analyzes impact of immunosuppressives on CV risk factors after renal transplants

Hospital Clinic, Barcelona - Heparin coating improves biocompatibility and reduces area of platelet mass

Hospital for Sick Children, Toronto - Contractility at basal heart rate is depressed in univentricular hearts

Hospital Italiano de Buenos Aires - Isometric exercise increases LVEDP in patients with aortic stenosis

Hypertension Writing Group - Group urges doctors to go beyond blood pressure numbers in defining hypertension

Immersion Medical, Inc. - New modules of Endovascular AccuTouch System released

Indiana University - Adjunctive epithelial sodium channel inhibitors improve blood pressure control

Ingenix Inc. - Hyperlipidemia treatment in managed care setting remains in need of improvement

INSERM Centre de Recherche Cardiovasculaire Lariboisiere, Paris - p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling

Institut Pasteur - Researchers collaborate to learn how bacterium live in cold of Antarctic

Japan National Cardiovascular Center - Adrenomedullin regenerates alveoli and vasculature in elastase-induced pulmonary emphysema

Johns Hopkins University - Inhibition of xanthine oxidase can alter HF progression in dilated cardiomyopathy

Julius Center for Health Sciences and Primary Care, Amsterdam - Researchers provide overview of gene studies to identify underlying menopausal age

Kansai Medical University, Moriguchi City - Exercise training improved exercise tolerance after MI

Kaohsiung Medical University - Big ET-1 and ET-1 correlated with severity of HF in congenital heart disease

Karadeniz Technical University, Trabzon - Increased venous thromboembolism risk may be related to increased tPA levels

Karolinska Institute - Doppler tissue imaging may enhance estimates of diastolic dysfunction

Kyoto University - Mitochondrial impairment is induced in cortical neurons after oxygen and glucose deprivation

Kyushu University, Fukuoka - Excess L-Arg restores impaired endothelium-dependent relaxation

Laiko Hospital, Athens - ESS/ESD slope is a sensitive contractility index

Lawrence Livermore National Laboratory - Dynamics of lipid metabolism can be monitored using Raman spectroscopy

London Health Science Center - Researchers try to determine causes of cardiac allograft rejection

Massachusetts General Hospital - C4d staining can establish criterion for antibody-mediated cardiac rejections

Massey University - Exercise improves cardiopulmonary fitness in asthma patients

Matria Healthcare - Disease management company wins six new accounts and four account expansions

Mayo Clinic - Assessment of segmental relaxation may be beneficial in hypertensive patients

Mayo Clinic - Insight may be valuable tool for diagnosing constrictive pericarditis

Mayo Clinic - Study results suggest better outcomes with drug-eluting stent than with brachytherapy

Mayo Clinic - Tissue Doppler, strain rate imaging offer quantification of regional myocardial function

Medical Simulation Corporation - Simulation provider introduces training product for carotid stenting

Medical University of Bialystok - Gastroesophageal reflux disease may provoke myocardial ischemia

Medtronic Inc. - Polyether polyurethanes with PEO SMEs delay biodegradation, retain biostability in vivo

Medtronic, Inc. - Study to evaluate performance of drug-eluting coronary stent system

Merck Research Laboratories - Podocarpic acid amides are potent agonists for receptors in cholesterol metabolism

Monash University - Testosterone therapy improves sexual function in post-menopausal women

Mount Sinai School of Medicine - Fibrin-targeted contrast agent improves MRI thrombus detection

Myriad Genetics, Inc. - Biopharma company nears completion of preclinical data on antithrombin drug

Nagoya City University - Study revealed new mechanism for cardioprotective effects of 17 beta-estradiol

National Taiwan University Hospital - Study provides molecular basis of NO as negative regulator in ET-1-induced cardiac hypertrophy

National University of Singapore - Transduced myoblasts prompt endothelial cells to form vessel-like structures

North Shore University Hospital, Manhasset - Histones may be cofactors in T3 regulation of cardiac alpha-MHC transcription

North-West University, Potchefstroom - Consumption of nuts may significantly decrease cholesterol

Northwick Park Hospital & Clinic Research Center, Harrow - Contrast echo can be used to detect coronary artery disease in patients presenting with heart failure

Otto Von Guericke University, Magdeburg - Stimulated expression of dentate gyrus granule cell mu-opioid receptor occurs after focal ischemia

Papworth Hospital, Cambridge - Heart transplants provide survival benefit with rigorous donor and recipient selection

Patient Education - Self-directed CPR learning program available

Polish Air Force Institute of Aviation Medicine - Decreases in antioxidative enzymes may play key role in artherogenesis

Polytechnic University of the Marche Region Medical School, Ancona - Vascular endothelial growth factor differentiates clear cell renal carcinomas

POZEN, Inc. - Trexima NDA accepted for review by U.S. Food and Drug Administration

Queen's University, Kingston - p21-activated kinase induces podosome formation in vascular smooth muscle cells

Quest Diagnostics - Average LDL cholesterol levels decreased 10% in people under doctors' care from 2001 to 2004

Radiant Medical, Inc. - Medical technology company raises $36 million toward heart research

Recom Managed Systems - Life sciences company appoints Keitt and Sosebee to cardiac services division

Reliant Pharmaceuticals, Inc. - Pharma company launches lipid-regulating drug in U.S.

Robarts Research Institute - CDN $2.6M grants made for cardiology research in Canada

Royal Free & University College Medical School, London - Inflammation and hemostasis may increase cardiovascular risk from smoking

Sapporo Medical University - Novel scoring system predicts prolonged hypotension after carotid stenting

Schering AG - European Commission approves magnetic resonance angiography contrast agent

Scios - Pooled trial data on nesiritide presented at Heart Failure Society meeting

Sheba Medical Center, Tel Aviv - Cardiac valve pathology may be risk factor for several types of CNS involvement

Shiraz University of Medical Science - Low 5-methyltetrahydrofolate was associated with severity of CAD

Showa General Hospital, Tokyo - Technique reliably measures blood flow volume and artery diameter

Sorin Group - New generation cardiac resynchronization therapy products introduced at meeting

Southwest Foundation for Biomedical Research - Researchers discover gene on chromosome 15 that regulates inflammation

Spectranetics Corporation - Colorado laser technology company named top performer in Technology Fast 50 program

Speedel Pharmaceuticals, Inc. - Phase 1 safety, tolerability testing of renin inhibitor for hypertension started

St. Jude Medical, Inc. - New device closes heart defect, preventing unfiltered blood from entering circulation

St. Luke's Episcopal Hospital, Houston - Pravastatin therapy offers long-term benefits to heart transplant recipients

Stanford University - DDAH-I overexpression attenuated graft coronary artery disease

State University of New York Downstate - Suppressed fibrinolysis found in obese adolescents with type 2 diabetes

Surface Logix Inc. - Phase 1 trial of inhibitor to treat endothelial dysfunction achieves target profile

Taipei Medical University - Automaticity was more easily induced by Ba2+ in pulmonary veins than in left atria

Technion Israel Institute of Technology, Haifa - Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages

Tel Aviv University - WBC count is marker for stratification of ischemic cerebrovascular disease

Texas A&M University, College Station - Estrogen regulates contractile responses of female rat aorta to vasopressin

Thoraxcenter - Self-contained MRI catheter allows identification of vulnerable coronary plaque

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