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Heart Failure

Reports from University of Groningen advance knowledge in heart failure

Published in Cardiovascular Device Liability Week, October 28th, 2007

According to recent research from Netherlands, "'Background The SENIORS trial showed that nebivolol reduced the risk of death or cardiovascular (CV) hospitalization in elderly patients with heart failure (HF). We aimed to assess tolerability and dose-related effects of the beta-blocker nebivolol in elderly patients from the SENIORS trial."

"Patients assigned to nebivolol (n = 103 1) were classified into 4 groups, according to the dose achieved at the end of titration phase (maintenance dose): 0 mg (n = 74), low dose (1.25 or 2.5 mg, n = 142), medium dose (5 mg, n = 127), and target dose (10 mg, n = 688) and compared with those allocated to placebo (n = 1030). Age, sex...

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