New hypertension therapy study findings reported from Veterans Affairs Medical Center

Research findings, 'Thiazide diuretics, endothelial function, and vascular oxidative stress,' are discussed in a new report. According to recent research from the United States, "Increased endothelial production of reactive oxygen species and decreased nitric oxide bioactivity, associated with the upregulation of monocyte chemoattractant protein (MCP)-1 and lectin-like oxidized low-density lipoprotein receptor (LOX)-1, link hypertension with atherogenesis. We investigated whether the beneficial effects of thiazide diuretics are exclusively related to a reduction in the biomechanical stress of hypertension or are also endowed with pleiotropic vasculoprotective effects that are independent...

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