Abdominal Aortic Aneurysm
Boehringer Ingelheim GmbH details research in abdominal aortic aneurysm
Published in Cardiovascular Device Liability Week, May 4th, 2008
"In this study, we examined the effects of overexpression of a natural inhibitor of uPA, plasminogen activator inhibitor-1 (PAI-1), on the development of angiotensin (Ang) II-induced AAA in ApoE-deficient (ApoE (/) ) mice. Mice were treated with recombinant adenovirus containing either the human PAI-1 gene (Ad5. CMV. PAI-1) or the luciferase gene...
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