Surgery

New surgery research from Y. Iwata et al outlined

Published in Cardiovascular Device Liability Week, May 4th, 2008

According to a study from the United States, "Aprotinin is used in cardiac surgery for its anti-inflammatory and hemostatic benefits. Recent reports describe the neuroprotective effects of other serine protease inhibitors via reduced excitotoxic cell death, a common pathway causing cytotoxic edema induced in various neuropathologic conditions."

"The purpose of this study was to investigate whether aprotinin directly protects against glutamatergic excitotoxicity in cell cultures. Mixed cortical cultures containing neuronal and glial cells were prepared from fetal mice at 13 to 15 days' gestation and plated on a layer of confluent astrocytes from 1- to 3-day-old postnatal...

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Source: Cardiovascular Device Liability Week (2008-05-04)

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