Transfusion Medicine
New transfusion medicine research from M. Mamtani and colleagues discussed
Published in Cardiovascular Device Liability Week, July 13th, 2008
According to a study from the United States, "Iron chelators have dramatically prolonged the life expectancy of patients with transfusion-dependent thalassaemia, but their precise clinical benefit in reducing the myocardial iron burden and improving cardiac function is unknown. This systematic review and meta-analysis included published clinical trials that assessed the efficacy of iron chelators in regularly transfused patients of thalassaemia major for two commonly reported outcomes - myocardial iron content and left ventricular ejection fraction (LVEF)."
"The meta-analysis of 392 patients for myocardial iron content and 291 patients for LVEF showed that (i) iron...
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