Restenosis

Researchers at Washington University publish new data on restenosis

Published in Cardiovascular Device Liability Week, July 20th, 2008

According to recent research from the United States, "Drug eluting stents prevent vascular restenosis but can delay endothelial healing. A rabbit femoral artery model of stenosis formation after vascular injury was used to study the effect of intramural delivery of alpha(v)beta(3)-integrin targeted rapamycin nanoparticles on vascular stenosis and endothelial healing responses."

"Femoral arteries of 48 atherosclerotic rabbits underwent balloon stretch injury and were locally treated with either (1) alpha(v)beta(3)-targeted rapamycin nanoparticles, (2) alpha(v)beta(3)-targeted nanoparticles without rapamycin, (3) nontargeted rapamycin nanoparticles, or (4) saline....

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Source: Cardiovascular Device Liability Week (2008-07-20)

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