Published in Cardiovascular Device Liability Week, October 26th, 2008
"We tested whether sevoflurane postconditioning produces cardioprotection via an ERK1/2-depen-dent mechanism. In protocol 1, Langendorff-perfused Sprague-Dawley rat hearts (n=84, 12 per group), with the exception of the Sham group, were subjected to 30 min ischemia followed by 90 min reperfusion and were assigned to the untreated (control) group, followed by 4 cycles of ischemic postconditioning (25 s of each),...
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