Published in Cardiovascular Device Liability Week, April 19th, 2009
"We used intravital microscopy of rat cremaster muscle microcirculation to track intraarterially delivered MSCs. Rat MSCs ( average diameter, 23 mu m) were bolused into the ipsilateral common iliac artery. Interrogation of an arteriole-venule pair revealed that 92 +/- 7% ( n = 6) of MSCs arrest and interrupt flow during first pass at the precapillary level, resulting in decreased flow in the feeding arteriole ( velocity decreased from 6.3 +/- 1.0 to 4.6 +/-...
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