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Aging

Findings from Medical Academy advance knowledge in aging

Published in Cardiovascular Device Liability Week, April 26th, 2009

According to recent research from Warsaw, Poland, "The extracellular matrix (ECM) undergoes constant dynamic changes; proteolytic enzymes, particularly the serine proteases plasmin, trypsin and elastase, catalyze critical functions in these processes. Notably, ECM degradation disorders have been reported in various morbid conditions, including cardiac infarction, atheromatosis, and neoplastic diseases, indicating a physiological requirement for proper ECM maintenance."

"Here we define the role of proteolytic enzymes in the development of aging by assessing changes in proteolytic enzyme activity in serum during aging in rats. The activities of trypsin, elastase and...

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