Hypercholesterolemia
Reports from University of Pennsylvania, Institute for Medicine and Engineering advance knowledge in hypercholesterolemia
Published in Cardiovascular Device Liability Week, February 7th, 2010
Scientists discuss in 'Hypercholesterolemia induces side-specific phenotypic changes and peroxisome proliferator-activated receptor-gamma pathway activation in swine aortic valve endothelium' new findings in hypercholesterolemia. "Background-The endothelium of healthy aortic valves expresses different phenotypes on the aortic and ventricular sides. On the aortic side, which is susceptible to aortic valve sclerosis, there is a balanced coexpression of both propathological and protective pathways," scientists writing in the journal Arteriosclerosis, Thrombosis, and Vascular Biology report.
"Side-specific global gene expression can address endothelial phenotype...
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