Heart Disease Risk Factor

Elevated soluble E-selectin indicates increased heart disease risk

Published in Cardiovascular Week, November 3rd, 2003

Obese patients with the angiotensin-converting enzyme gene polymorphism and elevated levels of soluble E-selectin have an increased risk for cardiovascular disease.

"Fifty-six young central obese patients were investigated to evaluate relationships between soluble E-selectin (sE-S), angiotensin-converting enzyme (ACE) gene polymorphism, left ventricular function and structure, and carotid morphology by determination of sE-S and ACE genotypes," scientists in Italy report.

"Our results indicated that central obese subjects with concomitant higher levels of sE-S and ACE DD genotype may be characterized by early cardiovascular alterations and then...

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Source: Cardiovascular Week (2003-11-03)

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