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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . November 17th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Acute Myocardial Infarction - Aspirin withdrawal may pose risk to coronary patients

Cardiac Sarcoidosis - Cardiac sarcoidosis goes from a Th1 to a Th2 cytokine profile with cure

Cardiology - Hepatitis C virus may play a role in hypertrophic cardiomyopathy formation

Coronary Artery Bypass - MSCTA is promising method for lesion detection in coronary artery bypass grafts

Heart Transplant Risk - Transplant related coronary artery disease is linked to TNF-alpha, IFN-gamma

Abdominal Aneurysm - New anesthesia for morbidly obese patients with aortic aneurysm described

Acute Coronary Syndrome - Physical exams crucial in assessing risk level of acute coronary syndrome

Adhesions - Company launches new product development program based on RTG technology

Aging - Undetected heart disease may be linked to poorer health in later years

Angiology - Magnetic resonance angiography for vascular disease diagnosis reviewed

Angiology - Superoxide anion involved in endothelin-induced chronic hypertension

Angioplasty - FDA advises physicians of adverse events associated with Cordis Cypher

Atherosclerosis - MRI aids study of atherosclerotic plaque rupture and arterial occlusion

Atherosclerosis - Oxidized LDL induces calpain-dependent cell death in endothelial cells

Atherosclerosis - Positive phase II results reported on cholesterol management vaccine

Atrial Fibrillation - Phase I trial of ATI-2042 initiated

Autoimmune Disease - Pulmonary-renal syndrome is a life-threatening risk from autoimmune disease

Awards - Lenfant receives lifetime achievement award from chest physicians

Biotechnology - Optimal surface topography for cardiac myocyte culture determined

Blood Pressure - Non-invasive blood pressure monitor studied for emergency department use

Cardiac Prediction Models - Blues of Michigan recognized for partnerships to improve patient care

Cardiology - Altered sodium/calcium ion exchange strongly affects total SR Ca2+ load during heart failure

Cardiology - Company reports European approval and first implant of new CRT-D

Cardiomyopathy - Cardiac mitochondria may be key in doxorubicin-induced cardiac failure

Cardiovascular Devices - New recommendations issued on treating device infections

Cardiovascular Disease - Effect of anemia on CVD risk clarified

Cardiovascular Disease - Erythropoietin treatment improves cardiac function after heart attack

Cardiovascular Disease - Gene mutations have differential effects on cardiac function, heart failure risk

Cardiovascular Disease - Grant helps development of therapeutic agent to treat cardiovascular diseases

Cardiovascular Disease - Magnetic resonance imaging for congenital heart disease monitoring reviewed

Cardiovascular Disease - Normal testosterone levels may lower atherosclerosis risk

Cardiovascular Disease - Obesity linked to vascular stiffness in young adults

Cardiovascular Disease - Spontaneous indices are poor measure of arterial baroreflex

Cardiovascular Disease - Testosterone antagonizes aortic smooth muscle cell calcium channels

Cardiovascular Drugs - Cardiovascular drugs in development are reviewed

Cardiovascular Gene Therapy - Adenoviral-transduced MSCs useful for eNOS gene transfer

Cardiovascular Medicine - Effects of estrogen on vascular system reviewed

Cardiovascular Medicine - Use of computed tomography for cardiac imaging reviewed

Carotid Artery Stenting - First human carotid artery cases successfully completed in Germany

Central Nervous System - Erythropoietin in CSF of patients with hemorrhage originates from brain

Chronic Angina - FDA committee scheduled to review Ranexa

Collaborations - Key strategic alliance announced for copolymer technologies

Congestive Heart Failure - Mitochondrial gene transcription suppressed during CHF

Coronary Artery Disease - British health authority recommends use of drug-eluting stents

Development - Embryonic p300 acetyltransferase activity needed for heart, lung and small intestine formation

Developmental Biology - Identification of "jelly belly" gene may lead to new drugs

Diabetic Nephropathy - Losartan delays progression of renal disease in diabetic patients

Diet and Nutrition - Docosahexaenoic acid in fish protects against cardiovascular disease

Diet and Nutrition - Myocene-like diet significantly reduces cholesterol levels

Drug Delivery - Xcelovair, a dry powder inhaler technology, licensed to Pfizer

Employee Health - MetLife research highlights top five workplace disabilities

Finance - Cardiovascular device company reports 12% increase in revenue

Finance - Company sees third revenue decline, reports BCI acquisition

Genetic Disorders - Cardiac sodium channel gene mutations underlie sick sinus syndrome

Glomerulonephritis - Rapidly progressive glomerulonephritis must be diagnosed using serology, biopsy

Heart Attack - Pyruvate and acetoacetate provide antioxidant protection to post-ischemic heart

Heart Defects - Mini-incisions mean less pain, scarring, less infection, faster recovery

Heart Disease - Clinic says new diagnostic test predicts cardiac risk up to 6 months ahead

Heart Disease Risk - ApoB a better marker than "bad" cholesterol

Heart Disease Risk - Child care may be hazardous to grandma's health

Heart Disease Risk - Interleukin-6 may be best marker for heart disease, stroke in elderly

Heart Disease Risk - Some LDL cholesterol particles are worse than others

Heart Transplantation - Atrial size linked to long-term survival after orthotopic heart transplantation

Heart Valves - 10-year clinical data presented for stentless tissue heart valve

Heart, Kidney Transplantation - FDA issues approvable letter for Certican

Hematology - Nematode anticoagulant protein targets blood coagulation factor

Hematology - Novel preparation of heparins specific to factor Xa reported

Hypercholesterolemia - Allelic variations in promoter region of LDL receptor gene reported

Hypertension - Angiotensin II likely plays limited role in menopause-related hypertension

Hypertension - Angiotensin II-induced ROS play role in cyclosporine A-induced hypertension

Hypertension - Beta-blockers inappropriate as first-line hypertension treatment?

Hypertension - Cannabinoid receptor CB1 mediates hypotensive effect of ET-1 during NOS inhibition

Hypertension - Individual cardiovascular response to sodium intake highly variable

Hypertension - Mild high blood pressure helps elderly's cognitive skills

Hypertension - Team approach works better to reduce blood pressure in African American men

Infection Prevention - Catheter medication clinical trial to begin

Kidney Disease - Kidney patients at highest risk for heart disease

Kidney Function - Vascular permeability factors may play a role in kidney disease

Lipid Studies - Minimally modified LDL is an oxidized LDL enriched with oxidized phosphatidylcholines

Market Analysis - Blockbuster drugs to lose market share over next decade

Medical Devices - CareStation 126s receives 510K clearance from FDA

Mergers and Acquisitions - Complient acquired by cardiology company

Mergers and Acquisitions - Historical Autographs U.S.A. to acquire biomedical device company

Mergers and Acquisitions - Medamicus closes acquisition of assets of Minneapolis, Minnesota, company

Non-Hodgkin Lymphoma - Biopharma company commences a phase II study for Pixantrone

Obesity Epidemic - Study implicates obesity as major killer

Obstetric - Pre-eclampsia-induced heart failure treated with anti-hypertensive drugs

Personnel - Kevin Swiss, PhD, named associate director, regulatory consulting

Pulmonary Disease - Potential treatment studied for patients with wasting associated with COPD

RNA Interference - Milestone achieved in simultaneously disabling multiple genes

Stem-Cell Research - Neural crest stem-cell defects in TrkC null mice identified

Stroke - Treadmill exercise may suppress hippocampal apoptosis following stroke/ischemia

Sudden Cardiac Death - Company announces U.S. launch of implantable defibrillator

Sudden Cardiac Death - Smoking increases SCD risk in patients with heart disease

Systemic Lupus Erythematosus - Study shows increased risk factors for heart disease among women with lupus

Thrombosis - Curacyte awarded grant to fund development of factor Xa inhibitors

Thrombosis - Research shows link between roving blood vessel cells, circulatory system damage

Vascular Health - JAK2 enzyme helps protect brain cells, wreaks havoc on blood vessels

Vessel Harvesting - Guidant licenses tissue welding technology for cardiac surgery

Weight Control - A town called Calcium trims down with dairy

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