Atherosclerosis

DHEA increases macrophage foam-cell formation

Published in Cardiovascular Week, January 12th, 2004

Dehydroepiandrosterone (DHEA), a sex hormone precursor available over-the-counter in the United States and often promoted as an "anti-aging" supplement, may promote the formation of fatty plaques in arteries, according to a new laboratory study.

"Our lab study shows a surprising result that DHEA may promote coronary disease, rather than prevent it, and while it is a lab result, it does suggest that caution should be taken in the unsupervised self-administration of the hormone. It seems to suggest to us that any administration of DHEA in humans at the moment should probably be restricted to the context of research, rather than over-the-counter use," said Martin K.C. Ng,...

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Source: Cardiovascular Week (2004-01-12)

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