Stem-Cell Research

Hematopoietic stem cells adopt mature hematopoietic fates in ischemic myocardium

Published in Cardiovascular Week, May 31st, 2004

Hematopoietic stem cells adopt mature hematopoietic fates in ischemic myocardium.

"Under conditions of tissue injury, myocardial replication and regeneration have been reported. A growing number of investigators have implicated adult bone marrow (BM) in this process, suggesting that marrow serves as a reservoir for cardiac precursor cells. It remains unclear which BM cell(s) can contribute to myocardium, and whether they do so by transdifferentiation or cell fusion," wrote scientists at Stanford University.

We "studied the ability of c-kit-enriched BM cells, Lin^- c-kit⁺ BM cells and c-kit⁺ Thy1.1^lo...

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Source: Cardiovascular Week (2004-05-31)

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