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Cardiology

Understanding metabolism derangements will enable new pharmacological approaches

Published in Cardiovascular Week, September 13th, 2004

A recent report questions whether the metabolic approach an appropriate one for recurrent and resistant angina.

"Chronic stable angina is the first manifestation of ischemic heart disease in one half of patients; in the United States, the annual incidence of angina in 213 of 1000 of the population is over 30 years of age. The morbidity associated with ischemic heart disease is considerable: each year millions of patients have an MI, or are hospitaliZed for unstable angina," wrote M. Marzilli of the University of Siena.

"In recent years less attention has been paid to chronic ischemic syndrome; a possible explanation is that most patients with angina,...

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