Cardiovascular Week
Susan Hasty, Publisher
Table of Contents . . . October 4th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cardiovascular Week | Other Publications
Angiology - Combination may provide a potential treatment of arterial thrombotic disorders
Cardiotoxicity - Carbon monoxide may have two independent cardiotoxic effects
Cholesterol Research - Clinical benefit of statin-induced elevation of HDL-cholesterol is unclear
Hypertension - Perinatal factors could program an individual for risk of cardiovascular disease
Psychological Stress - Changes in rats correspond to changes relevant to CV diseases in humans
Anesthesia - Hazards of surgery and anesthesia for drug, alcohol abusers presented at meeting
Anesthesiology - Patients with cardiac RyR defects had general anesthesia without complications
Angiology - Cellular mechanisms that control regulation of TASK-1 by PAF are examined
Angiology - Glycoproteins have a procoagulant role in collagen-dependent thrombus formation
Angiology - New treatments may soon include agents known as the metabolic modulators
Angiology - Responses to BK of peripheral arteries and coronary arteries correlated
Angiology - Serial surveillance of patients is vital after arterial switch operation
Angiology - Slowed VO2 kinetics occur only with exercise of the affected limbs
Angiology - Vascular and valvular calcium levels linked
Angiology - aPT IgG is a significant marker for deep vein thrombosis/pulmonary embolism
Angiotensin - Gene-targeting experiments have elucidated AT1 receptor functions
Angiotensins - Chymase and carboxypeptidase A have key roles in generating and degrading Ang II
Aortic Regurgitation - Conservative surgery suggested when isolated lesion causes aortic regurgitation
Arrhythmia - Study addresses concern about association with ventricular tachyarrhythmias
Artificial Heart - Smaller driver for artificial heart licensed by cardiac device company
Atherosclerosis - Contributions of the A3 AR do not control vascular response to injury
Atherosclerosis - Improved understanding of atherogenesis has resulted in assessment techniques
Atherosclerosis - Paired iliac artery stent model helps determine drug-delivery device effect
Atherosclerosis - Vascular grafting is effective in revascularization
Atherothrombosis - Inhibition of tissue factor can improve outcomes in atherothrombosis
Awards - Defibrillator manufacturer receives leadership award for product line
Biosynthesis - Researchers identify a cardiolipin-remodeling enzyme in the mouse
Blood Pressure Monitoring - ABP monitoring can ease obstacles of obtaining accurate BP in dialysis patients
Business & Finance - Medical technology company acquires assets of Coalescent Surgical
Business Update - Company announces US$24.4 million in sterols sales agreement
Business Update - Company focuses on regenerative medicine, sells blood conservation technology
Business Update - Electrophysiology company enters relationship with Partners Equity Capital
Business Update - Medical-technology company establishes U.S. operations
Business Update - NitroMed up; to present trial data at conference
Calcium Channel Blockers - Different calcium channel blockers exert different effects on MMP-2 expression
Cardiac Aging - Supplemental carnitine and lipoic acid improve the glutathione redox system
Cardiac Arrest - Cardiovascular drug cuts sudden cardiac death by 21%
Cardiac Arrest - Efficacy of biphasic defibrillators compared
Cardiac Arrest - Training key to defibrillator success
Cardiac Arrest - Where are we going with community defibrillation?
Cardiac Development - NT-3 may be important for cardiac development
Cardiac Function - Maintaining baroreflex function during 6 months of CyA treatment may be pivotal
Cardiac Hypertrophy - A3243G mtDNA mutation is linked to abnormal heart energetics and cardiomyopathy
Cardiac Side Effects - Alemtuzumab may have a role in inducing important cardiac side effects
Cardiac Surgery - Authors review cases of cardiothoracic surgery performed on Jehovah's Witnesses
Cardiac Surgery - Midazolam was a more effective antiemetic than ondansetron
Cardiology - Angiogenesis fosters the formation of aortic valve stenosis
Cardiology - C-reactive protein raises heart disease risk by impairing angiogenic function
Cardiology - Cannabinoid depresses respiration and enhances sympathetic tone and vagal tone
Cardiology - Cx43 and Cx45 connexins form diverse channels
Cardiology - Echocardiography is key to discussing indications for and timing of surgery
Cardiology - Effects of chronic hypoxia are described
Cardiology - Lysophosphatidic acid stimulates the adventitia to produce adrenomedullin
Cardiology - Mild exercise training does not increase MCT4; causes complex changes in MCT1
Cardiology - No evidence reported for phospholipase D activation by GI or IPC
Cardiology - Troponin sense and antisense interactions form the basis for a new hybrid RNA
Cardioprotection - Epo has untapped potential in cardiac treatment
Cardioprotection - Statins mobilize endothelial progenitor cells to improve cardiac function
Cardiovascular Calcification - Calcium-free products bind phosphate without cardiovascular calcification
Cardiovascular Care - Cardiac rehab keeps heart patients fit, healthy
Cardiovascular Development - Endoglin plays a key role in cardiovascular development and vascular remodeling
Cardiovascular Devices - Radiological peritoneovenous shunt insertion feasible for intractable ascites
Cardiovascular Disease - Animal health company launches trials on dogs with heart diseases
Cardiovascular Disease - Giant coronary artery aneurysm rupture due to Kawasaki disease reported
Cardiovascular Disease - Par Pharmaceutical enters marketing agreement to its nitroglycerin lingual spray
Cardiovascular Disease - Treatment of intrastent restenosis reviewed
Cardiovascular Health - CV capacity, quadriceps muscle strength play modest role in rapid walking
Cardiovascular Health - Hemostatic factors did not correlate with functional TAFI levels in plasma
Cardiovascular Modulation - Medial prefrontal cortex has excitatory action on the sympathetic nervous system
Cell Development - ZNF394 may play an important role in cardiac development, function
Cell Research - Ligusticum chuanxiong and Angelica sinensis protect ECV304 cells
Cholesterol Homeostasis - NPC1L1 may be useful for treating hypercholesterolemia and sitosterolemia
Chronic Obstructive Pulmonary Disease - COPD patients prefer Respimat Soft MistTM Inhaler
Chronic Obstructive Pulmonary Disease - New research targets management of COPD
Chronic Obstructive Pulmonary Disease - Oxygen supplementation seems to be a promising treatment
Clinical Trials - Phase 2 protocals submitted to U.S. FDA for clinical trials of synthetic blood
Collaborations - Diagnostics company enters broad diagnostic collaboration with Compugen
Complementary & Alternative Medicine - Kiwifruit and aspirin have similar effects for heart health, study shows
Complementary & Alternative Medicine - Patient education about kava use in the perioperative period is suggested
Complementary and Alternative Medicine - Hibiscus flowers may prevent heart attacks
Congenital Heart Block - Autopsy slides may provide clues to pathogenicity of maternal autoantibodies
Congenital Heart Disease - BNP concentration may be a useful tool in managing congenital heart disease
Congestive Heart Failure - CD4+ and CD8+ are altered in dogs with congestive heart failure
Congestive Heart Failure - Company reports oxypurinol clinical results
Congestive Heart Failure - Inhibition of aldosterone is warranted in congestive heart failure and hypertension
Congestive Heart Failure - Older women with heart disease, diabetes have triple the risk of heart failure
Congestive Heart Failure - Prolonged, sustained exercise prevents precursor to heart failure
Coronary Artery Bypass - Interrupted distal anastomosis uses clips instead of sutures
Coronary Artery Bypass Grafting - Novel variation of radial artery described
Coronary Artery Disease - FDA approves small vessel cobalt chromium coronary stent
Coronary Artery Revascularization - Changes must be embraced for improved outcomes after coronary revascularization
Coronary Bypass - Statin therapy is beneficial to patients undergoing coronary revascularization
Coronary Lesions - FDA conditional approval granted to use Petal Stent System in BOSS trial
Coronary Syndrome - Two classes of indicators are under investigation
Coronary Syndromes - Knowledge of components of remodeling provide potential therapeutic targets
Critical Limb Ischemia - Utility of excimer laser-assisted angioplasty reviewed
Dental Health - Oral surgeons explore anesthesia care for complex patients at conference
Dermatology - Treatment of chronic venous leg ulcers trial results announced
Diabetes - Combination therapy of AVANDIA plus Metformin proven effective for diabetics
Diagnostics - BNP can be used to differentiate causes of respiratory distress in children
Diagnostics - Platelet function can predict heart damage in acute MI patients, study shows
Dialysis - Time-integrated analysis should be used to examine all parameters concurrently
Diet & Nutrition - Eating fish helps slow atherosclerosis in women, especially those with diabetes
Drug Development - Aprotinin injection during artery bypass graft surgery may reduce risk of stroke
Drug Development - Collaboration agreement signed for development of non-antibody protein
Dyslipidemia - Crestor reaches 10M prescription milestone
Echocardiography - Cornell criteria are best for males; Sokolow-Lyon criterion best for females
Embryology - Retinol deficiency mars embryonic vessel growth by hindering angioblasts
Epidemiology - Inhalation of particular matter can increase cardiovascular disease incidence
Fabry Disease - Company successfully completes phase IV study of Fabrazyme
Finance - Early-stage pharmaceutical announces $1M grant, 2 new hires
Fontan Circulation - Patients with Fontan circulation have a progressive reduction of HRV over time
Genomics - A substantial genetic component to pulse pressure is identified
Heart Attack - Clinton was a "vulnerable patient"
Heart Disease - "Bill Clinton Effect" substantiated by bio-surveillance system
Heart Disease - Benefits of EECP therapy for heart disease presented
Heart Disease - Enrollment completed for trial studying unnecessary right ventricular pacing
Heart Failure - Expanded indication for cardiac resynchronization therapy defibrillators
Heart Failure - FDA approval sought for AbioCor replacement heart
Heart Failure - Myocytes with normal sinus rhythm were clearly differentiated
Heart Failure - SERCA2a restoration ignites transcriptional changes in the failing heart
Heart Rhythm - Power spectral analysis of heart rate variability is a useful method
Heart Surgery - Mended Heart's volunteers offer help to recovering heart surgery patients
Heart Transplantation - Thymic injection of anti-Fas mAb improves cardiac graft survival
Heart/Lung Function - Cardiovascular responses to hypergravity depend on the posture of the subject
Hemochromatosis - Bilirubin may counteract the effect of oxidative stress from iron overload
Hypercholesterolemia - Data supports Fluvastatin's renal safety profile in high-risk patient population
Hypercholesterolemia - Rosuvastatin lowers asymmetric dimethylarginine in hypercholesterolemia
Hypertension - AT2 receptor results in lower blood pressures
Hypertension - Atorvastatin prevents end-organ injury in a salt-sensitive hypertension model
Hypertension - Baseline and approaches to data analysis of hypertension trial presented
Hypertension - Clinical study to evaluate HCT 3012 effects on blood pressure initiated
Hypertension - Company announces priority review designation for Ventavis NDA
Hypertension - Control of extracellular volume and sodium normalize BP in dialysis patients
Hypertension - Effects of CYP11B2 and AT1R on heart rate depend on sodium excretion
Hypertension - Interventions to curb CV mortality of ESRD should target hypertension and LVH
Hypertension - Intravenously and subcutaneously administered treprostinil are bioequivalent
Hypertension - Notice of allowance received for synthetic, nonpsychotropic cannabinoids
Hypertension - Nutritional antioxidants have beneficial effects in stroke-prone rats
Hypertension - Physicians want methods to integrate hypertension trial results into practice
Hypertension - Prolonged and frequent dialysis permits better control of hypertension
Hypertension - Researchers find new yogurt lowers high blood pressure
Hypertension - The renal medulla plays a pivotal role in long-term regulation of blood pressure
Hypertension - Transgenic models give a better understanding of the renin-angiotensin system
Hypertrophic Obstructive Cardiomyopathy - Left ventricular apex epicardial pacing can be effective for HOCM patients
Hypoxic Apnea - Thermal stress prevents autoresuscitation from hypoxic apnea
Imaging - Molecular imaging annual meeting highlights ability to view disease in vivo
Imaging - Systolic mitral annulus velocity not a reliable index of contractile performance
Imaging - Technique replaces intra-arterial digital subtraction angiography
Immunotherapy - Multikine immunotherapy drug lowers cholesterol in cancer study patients
Ischemia - Blocking the JNK pathway may be novel approach for treating myocardial ischemia
Isoforms - Fudion protein can promote myofibrillogenesis in hearts lacking tropomyosin
Limb Ischemia - Potential approaches to problems of critical limb ischemia are discussed
Lipid Studies - APOE*2 antiatherogenic lipid pattern is detected in a highly admixed population
Long QT Syndrome - ICD therapy appropriate for pediatric patients
Lower Limb Ischemia - Subintimal angioplasty effective in many cases
Macular Degeneration - Investigational New Drug application filed for macular degeneration trials
Medical Devices - Children's Heart Center installs pediatric cardio data management software
Medical Devices - U.K. patient is first to receive implant of heart failure management device
Mental Health - Alexithymia may be linked to CVD via autonomic dysregulation process
Mergers and Acquisitions - Mobetron manufacturer and distributor to be acquired
Metabolic Syndrome - New data presented for Crestor in patients with metabolic syndrome
Mitral Valve Function - Viscoelastic properties of mitral valve chordae can be explained morphologically
Myocardial Infarction - Coronary angioplasty soon after medical therapy could be best treatment
Myocardial Infarction - Inflammatory marker may be early sign of blood vessel blockages
Myocardial Infarction - Sarafotoxin 6c reduces myocardial infarct size
Myocardial Infarction - Study examined the relation of atherosclerotic plaques to the onset of MI
Nutrition - Prize for modern nutrition from the Federation of Swiss Milk Producers awarded
Nutrition - Research shows almonds increase intake of several important nutrients
Obesity - LifeWise Heart Truth Challenge prize awarded
Obesity Epidemic - Environmental changes can reduce the obesity epidemic
Patents - Company granted European patent for DX-88
Patents - Medical technology company announces favorable patent infringement decision
Pediatric Cardiology - Repolarization abnormalities studied in children with structurally normal hearts
Pediatric Myocarditis - Study describes predictors of outcome of myocarditis in pediatric patients
Peripheral Arterial Disease - Patients with peripheral arterial disease are currently being undertreated
Peripheral Arterial Disease - Study reports on peripheral arterial disease related amputations
Pharmaceutical Research - Data on alternative for pulmonary arterial hypertension patients presented
Pharmacology - ME10092 cardioprotective effect may be mediated by modulation of NO production
Preeclampsia - Early changes in IGF-I synthesis in pregnancy may be involved in hypertension
Product Licensing - Company licenses exclusive rights to cinnamylidene-anabaseines compounds
Production Distribution - HemoSense inks distribution agreement for point-of-care coagulation diagnostics
Protein Kinase C - Agonists protect cells in vitro, exert little protection in an in vivo model
Protein Synthesis - Inhibition may be a key mechanism by which hypertrophic growth can be controlled
Pulmonary Arterial Hypertension - Enrollment target reached for STRIDE-2, pivotal phase III trial for Thelin
Receptor Kinases - GRK 3 may have a role as a negative feedback regulator
Renal Arteriovenous Fistula - Novel TAE technique devised for fistula closure
Renin - The diversity of renin actions is reflected by its complex control
Restensosis - Moderate alcohol consumption cuts rate of further narrowing after heart surgery
Rett Syndrome - Alteration of NGF levels may explain altered ventricular repolarization
Shortness Of Breath - CE Mark granted for new emergency department diagnostic test
Sleep-Related Breathing Disorders - Sleep-related breathing disorders are a prognostic factor after stroke
Sports Medicine - Anticipatory response ensures that thermal homeostasis is maintained
Stents - Company gives positive report of AMS at 6 months follow-up
Stroke - FDA approves new carotid stent system
Tachycardia - The clinical approach should always consider the clinical context of arrhythmia
Thrombogenesis - The platelet integrin alphaIIb beta3 has three-dimensional features
Thrombosis - Guidelines offer new recommendations for travelers
Toxicology - Aprotinin protects against BT venom-induced cardiopulmonary toxicity
Transfusion - Acute lung injury is the third most common cause of transfusion-associated death
Trends - Cholesterol drugs may open door for more OTC switches
Vasodilators - Cellular mechanisms underlying relaxant effect of urocortin are characterized
Ventricular Tachyarrhythmia - ICD treatment may not prevent postoperative recurrence
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