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Angiotensin

Gene-targeting experiments have elucidated AT1 receptor functions

Published in Cardiovascular Week, October 4th, 2004

A recent report describes experiments with type I angiotensin (AT1 ) receptor functions through gene targeting

According to recent research published in the journal Acta Physiologica Scandinavica, "The renin-angiotensin system (RAS) modulates a diverse set of physiological processes including development, blood pressure, renal function and inflammation. The principal effector molecule of this system, angiotensin II, mediates most of these actions. The classically recognized functions of the RAS are triggered via the type 1 (AT1 ) class of angiotensin receptors."

S.D. Crowley and colleagues of the Veterans Administration...

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