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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . February 21st, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Cardiovascular Research - Diuretic-based treatment prevents major cardiovascular events in the elderly

Cardiovascular Research - Swim training increases cardiac vagal effects

Hypertension - Article stresses importance of focus on lowering systolic blood pressure

Hypertension - Canadian program recommends assessment with ambulatory BP monitoring

Hypertension - Respect of hemodynamic conditions in anesthesia reduces ischemic complications

Abdominal Aortic Aneurysm - Federal task force now recommending aortic screening for smokers

Adipose Tissue - Paracrine role for adipose tissue in regulating arterial tone discussed

Alcohol - Muscle weakness, arrhythmias and LV dysfunction are chronic effects of alcohol

Alcohol Use - Women have a higher health benefit over men from alcohol use

Amyotrophic Lateral Sclerosis - Pattern of outflow to muscles may be similar to chronological changes at neurons

Anesthesia - Landiolol is safe and effective during maintenance electroconvulsive therapy

Aneurysm - Elderly male smokers should be screened for abdominal aortic aneurysm

Angina - Gene therapy used for heart patients with moderate to severe chest pains

Angiology - Arterial tortuosity syndrome is characterized by connective tissue abnormalities

Angiology - Liver X receptor agonists studied, inhibitory activities revealed

Angiology - Recent findings in angiology described

Anticoagulation Therapy - Ximelagatran is a promising anticoagulant to decrease risk of embolic events

Arrhythmia - Study proves catheter ablation safe for patients

Arthritis - Rheumatoid arthritis patients at higher risk for unrecognized heart disease

Artificial Heart - Compact centrifugal blood pump with magnetically levitated rotor devised

Atherosclerosis - Antibody against the fibronectin extra-domain B aids arterial plaque imaging

Atherosclerosis - Foam cells generated by hyperglycemia and hyperlipemia in rats

Atherosclerosis - Volunteers with PAD needed to test dietary supplement's effect on leg pain

Atrial Fibrillation - AF ablation is restricted to patients who have failed antiarrhythmic drugs

Atrial Fibrillation - Catheter-based treatment of atrial fibrillation reviewed

Atrial Fibrillation - First human case using AtriLaze Surgical Ablation System complete

Atrial Fibrillation - It is important to recognize drugs as potential cause of atrial fibrillation

Atrial Fibrillation - Review describes mechanisms behind atrial remodeling due to atrial fibrillation

Bariatric Surgery - New York hospital partners to launch surgical weight loss program

Beta Oxidation - 5-trans-tetradecenoyl-CoA accumulates in the mitochondrial matrix

Biventricular Pacing - Procedure enables complete device-lead hookup and pocket closure in the lab

Business & Finance - Drug development company reports fourth quarter and 2004 results

Business Update - Brenner Children's Hospital named to NIH Pediatric Heart Network

Business Update - Company unveils imaging technology for cardiac MR community

Business Update - Medical device company extends contract to supply hemostatic bandages

Business Update - Millionth Taxus Express2 coronary stent system implanted

Business Update - Prometra Programmable Implantable Pump receives CE mark

Business Update - Report: Cholesterol drugs still poised for OTC switch despite Mevacor setback

Business Update - ThermaFix tissue-treatment process launched

Cancer Mortality - Cancer, heart groups issue joint statement on cancer statistics report

Cardiac Development - Periostin is predominantly expressed in endothelium of ventricular trabeculae

Cardiac Hypertrophy - Normal cardiac growth may be cofactor in development of genetic cardiomyopathies

Cardiac Hypertrophy - Stress from long-term hypertrophy may cause myocytes to reenter the cell cycle

Cardiac Rehabiliation - Call for faster action to improve U.K. cardiac rehab services

Cardiac Resynchronization - Review describes issues involved in optimizing cardiac pacing

Cardiac Resynchronization - Review discusses indications and limitations of cardiac resynchronization

Cardiac Resynchronization - Study will focus on a refined atrial tachyarrhythmia prevention pacing algorithm

Cardiology - Cardiovascular device company comments on HeartMate II clinical study filing

Cardiology - Dental group awards Seal of Acceptance to defibrillator with instant feedback

Cardiology - Diuretics have an important place in preventing cardiovascular events

Cardiology - Eugenol depresses force, no effect on contractile machinery of cardiac muscle

Cardiology - Injecting atropine during dobutamine stress ECG safely decreases test duration

Cardiology - Mitral flow inversion after Valsalva maneuver is common in healthy subjects

Cardiology - Myocardial infarction models aid the study of post-infarction scar formation

Cardiology - New findings impact diagnostic, therapeutic strategies of sudden death syndromes

Cardiology - Oyster cells are a promising model for various bioassays

Cardiology - Prosthesis demonstrated excellent postoperative clinical status

Cardiology - Recent findings illuminate research in cardiology

Cardiology - Reports add new data to cardiology research

Cardiology - Researchers describe findings in cardiology studies

Cardiology - Researchers provide details of new studies and findings in the area of cardiology

Cardiology - Researchers report details of new studies and findings in the area of cardiology

Cardiology - Studies focused on cardiac function in Trypanosoma cruzi-infected mice

Cardiology - Study explored the in vivo physiological functions of p38alpha in mouse hearts

Cardiology - Study results suggest possibilities for inhibition of cardiomyocyte apoptosis

Cardiology - Subsarcolemmal cAMP levels are regulated by negative feedback involving PKA

Cardiology - Tei index evaluates drug-induced left ventricular function improvement

Cardiology - beta1 -AR stimulation increases PI3K activity in adult rat cardiomyocytes

Cardiomyopathy - Study investigated the mechanisms of apoptosis induced by high-dose alcohol

Cardiovascular Devices - Leakage flow rate and wall shear stress determined in biocentrifugal VAD

Cardiovascular Devices - Reinforcement feasible for cracked paracorporeal blood pumps

Cardiovascular Diagnostics - Transdermal ACh and local skin warming cause dose-dependent vasorelaxation

Cardiovascular Disease - Doctors underestimate women's heart risk

Cardiovascular Disease - Early life factors linked to adult blood pressure

Cardiovascular Disease - Effects of adrenergic agents on post-defibrillation arrest time studied

Cardiovascular Disease - High risk women are under-treated for high cholesterol levels

Cardiovascular Disease - Homocysteine levels may be affected by coffee consumption

Cardiovascular Disease - Phobic anxiety increases heart disease death risk among women

Cardiovascular Disease - Very late in-stent restenosis can present as acute myocardial infarction

Cardiovascular Disease Therapy - Role of antiarrhythmic surgery reviewed

Cardiovascular Research - Fatigue is associated with CV disease, may not be influenced by genetic factors

Cardiovascular Research - One-month-old harbor seals can sustain long-duration apneas

Cell Research - AMP-activated protein kinase senses both redox and phosphorylation potential

Cerebral Oxygenation - Acute normovolemic hemodilution can lead to a reduction in cerebral oxygenation

Cholesterol - Serum cholestenoic acid analyzed, potential role as marker demonstrated

Chronic Heart Failure - Trials shed light on using angiotensin receptor blockers to treat heart failure

Chronic Kidney Disease - CRP monitoring in chronic kidney disease deserves closer study

Clinical Trials - Neuro-inflammatory disease drug approved for phase 1 clinical development

Clinical Trials - Pilot trial of heart implant results 'very encouraging,' researcher says

Cold Hemagglutinin Disease - Cryofiltration apheresis effective as last-resort treatment

Collaborations - Cardiology partner named for U.S.

Collaborations - Cardiology-device company signs agreement for production of magnetic guidewires

Collaborations - Cigna joins WomenHeart in the fight against heart disease in women

Collaborations - Deal signed with Medinol to develop AP23573 drug-delivery stents

Collaborations - Pharmaceutical companies announce collaboration on osteoporosis treatment

Complementary & Alternative Medicine - Nonprescription plant-based drug to lower cholesterol introduced

Congestive Heart Failure - New bedside tool gauges mortality risk in heart failure patients

Congestive Heart Failure - Rheumatoid arthritis linked to excess risk of congestive heart failure

Coronary Artery Disease - Cardiac imaging is underused in women

Coronary Artery Disease - HR variability may not be cause of CV morbidity in patients with panic disorder

Coronary Artery Disease - The eNOS 4a/b polymorphism does not have a major impact on CAD

Coronary Artery Disease - Thrombospondin polymorphism studied, altered Ca2+ binding observed

Coronary Heart Disease - Women need earlier use of PCI

Crosslinking - Optimal crosslinking conditions determined for cholesterol removal from milk

Cytochrome C - Cytochrome c can be transformed into peroxidase that oxidizes phospholipids

Dementia - Cardiovascular risk factors in midlife linked to risk of dementia

Diabetes Therapy - Benzoxazole-containing thiazolidinedione derivatives synthesized

Diabetes Therapy - New research in the area of diabetes therapy detailed

Diabetes Therapy - Researchers' data advance diabetes therapy research

Diabetic Cardiomyopathy - Hyperglycemia does not alter state 3 respiration in type 1 diabetes

Diabetic Nephropathy - Renin-angiotensin system modulation protects vascular system

Diagnostics - Findings do not favor association between anatomic abnormalities and arrhythmia

Diagnostics - Heart imaging system a noninvasive alternative to diagnose, treat heart disease

Diagnostics - Optical images capture gene expression in the arteries

Diagnostics - Skin sterol test available for sale in Canada, U.S. markets

Diet & Nutrition - Additive may help chips lower cholesterol

Diet & Nutrition - Food company promotes potential heart healthy benefits of chocolate

Diet & Nutrition - Health-based natural products store announces additions, realignments

Diet & Nutrition - Liquid product to reduce "bad" cholesterol launched

Diet & Nutrition - Meat processor completes removal of transfat from retail and school products

Diet & Nutrition - Online nutrition tracking system uses camera phone to keep diary of diet

Diet & Nutrition - Review discusses factors affecting methionone metabolism

Diet & Nutrition - Treated orange juice retains vitamin C bioavailability of fresh juice

Disease Control - Report published on most prevalent, costly diseases in U.S.

Drug Development - Study offers additional experimental paradigm for analyzing NO-donor metabolism

Drug Research - Heparin cofactor II-deficient mice studied, antithrombotic activity revealed

Electrocardiography - Cardiology products developer adds new electrocardiograph to line

Electrophysiological Tests - Electrophysiologic investigations provide a window into cerebral function

Embryonic Stem Cell Research - Wnt11 facilitates ESC differentiation to Nkx2.5-positive cardiomyocytes

Environmental Health - Long-term exposure to air pollution hardens arteries

Environmental Health - Volcano smog advisory reissued for Northern Mariana Islands

Environmental Research - Regulated bradycardial response in limpets is associated with avoidance behavior

Fibrosis - Review provides information on fibrosis and small bowel carcinoid tumors

Finance - Angina-focused company reports strong Q4 and 2004 results

Finance - Medical device company reports 2004 results

Finance - Pharma company completes $43 million series C financing

Finance - Provider of medical devices for venous reflux disease reports 4Q 2004 results

Finance - Research company announces public offering of common stock

Finance - UT receives $5 million donation for stem cell research

Fitness - Just 30 minutes of exercise a day could reduce heart disease mortality

Fitness & Wellness - Family doctor loses 80 pounds, becomes fitness trainer, produces wellness video

Gene Research - von Willebrand factor studied, multi-effect mutation revealed

Genetic Disorders - Genetic and environmental factors may explain craniofacial in Marfan syndrome

Genomics - Polymorphism might contribute to increased risk of coronary artery disease

Genomics - Report describes expression of tilapia extracellular Ca2+-sensing receptor

Genomics - Researchers tout ability of genetic tests to avoid bad drug reactions

Genomics - ST2LV is a new soluble secreted variant of the ST2 gene product

Genomics - Study identified biochemical and genetic defect in L-2-hydroxyglutaric aciduria

Geriatrics - Article examines increased risk of death in elderly surviving spouses

Health Promotion - Online children's health web site offer tips on 2005 Dietary Guidelines

Health Promotion - Online diet site, Discovery Health Channel partner for National Body Challenge

Heart Attack - St. Louis selects AED provider

Heart Attack Risk Factors - Heart attacks linked to circadian rhythms and large breakfast intake

Heart Disease - Biopharmaceutical company releases results of clinical studies in hypertension

Heart Disease - Cardiovascular disease in diabetes reviewed

Heart Disease - Published study shows fingertip test identifies coronary disease at early stage

Heart Disease - Treatment of choice for ED in heart disease patients is sildenafil

Heart Disease - Washington DC VA Medical Center uses miniaturized bypass technology

Heart Disease Risk Factor - Toe blood pressure can identify lower extremity arterial disease

Heart Failure - Actin-capping protein is a therapeutic target in the management of heart failure

Heart Failure - Article summarizes findings relevant to heart failure trials

Heart Failure - Cardiac recovery system unloaded left ventricle, reduced afterload in model

Heart Failure - Clinical update provided on AB5000 circulatory support system

Heart Failure - First implantation of cardiac devices with home monitoring reported

Heart Failure - Temporary artificial heart cited as major advance in cardiovascular medicine

Hereditary Hemorrhagic Telangiectasia - Hepatic artery embolization effective for HHT patients with hepatic involvement

Hormone Replacement Therapy - New data illuminates research in hormone replacement therapy

Huntington Disease - Study investigated effects of Huntington disease on autonomic nervous system

Hyperhomocysteinemia - Plasma thiol concentrations were likely a result of thiol-disulfide exchange

Hyperlipidemia - Marine biomass company reports effects of Neptune Krill Oil on cholesterol

Hypertension - Healthcare organization launches program for women and heart disease

Hypertension - Pharma company acquires Cibacen and Cibadrex

Hypertension - Salt retention hormone important factor in African Americans

Hypertrophic Cardiomyopathy - ECGs should extend into midlife in families with hypertrophic cardiomyopathy

Hypoplastic Left Heart Syndrome - Research improves long-term treatment of severe heart defect in children

Hypoxia - K+ATP channels are involved in deleterious effects of chronic hypoxia

Imaging - Article reviews image acquisition and contrast injection in aortic dissection

Imaging - Dobutamine-CMR can assess risk levels for coronary events with high accuracy

Imaging - Image guidance increased success of surgical closure of coronary artery fistulas

Imaging - MRI should be used more often in fetal cardiology

Imaging - Mapping method provides information to assess LV endocardial displacement

Imaging - Multidetector-row CT offers accurate visualization of anomalous coronary anatomy

Imaging - Sequential MDCT sufficient for determining risk of heart disease

Imaging - System is a promising tool for quantification of regional myocardial strain

Ischemia - New findings in the area of ischemia described

Ischemia - Treadmill exercise may facilitate recovery after ischemic cerebral injury

Ischemia/Reperfusion - New findings in the area of ischemia/reperfusion detailed

Ischemic Heart Failure - Decreasing TNF levels in plasma or tissues does not improve cardiac function

Left Ventricular Systolic Dysfunction - Utility of prophylactic ICD therapy clarified

Legal Issues - Tobacco trial witness says industry knew of smoking dangers

Letter to the Editor - Grapefruit-drug interactions

Lipid Studies - Compositional variations of HDL affect the influence of paraoxonase-1 on CV risk

Lipid Studies - Database contains results from whole-genome scans of lipid-related phenotypes

Lipid Studies - Researchers publish new studies and findings in the area of lipid studies

Lipid Studies - Study describes impacts of low-fat diet and high-MUFA diet on HDL metabolism

Lipid Studies - Study investigated new variants of the apoB(4372-4392) peptide

Lipids - Hepatic steatosis may be caused by or associated with abnormal lipid metabolism

Lupus - Innovative research receives increased funding

Mergers & Acquisitions - Company specializing in cardiovascular therapy announces acquisition

Migraine - New study confirms effectiveness of nasal spray for migraine treatment

Mitochondrial Regulation - Cold acclimation increases aerobic energy production in turtle myocardium

Myocardia - Myocardial phospholipids adapt to modest chemical and physical perturbations

Myocardial Infarction - COX-2 inhibitor increases the risk of heart attack in elderly adults

Myocardial Infarction - Granulocyte colony-stimulating factor improves post-infarction cardiac function

Myocardial Infarction - New research provides insight into gene response following MI

Myocardial Infarction - Patient characteristics have changed over the past 25 years.

Myocardial Infarction - Patients with previous heart attacks may not benefit from pacemaker implant

Myocardial Infarction - Pharma company signs new agreement with AstraZeneca

Myocardial Infarction - Study analyzed frequency, variables associated with return to work after MI

Myocarditis - Interleukin-10 gene transfer protects rodent hearts from inflammation

Neuroscience - Symptoms of sympathetic nervous system may be defensive reactions against nausea

Obesity - Doppler waveform of hepatic veins in obese population examined

Obesity Pathogenesis - Ectopic fat storage may impair function of organs

Obstetrics - Hypertensive patients need education and prompt care

Obstetrics - Statins are teratogenic

Oncology - Hypoxia inducible factor-alpha and c-erbB-2 interact to intensify breast cancer

Organ Transplantation - Steroid dependency studied in pediatric heart transplant patients

Osteoporosis - Fracture risk is increased in perimenopausal women treated with beta-blockers

Oxidative Stress - Biochemical changes in cold-induced oxidative stress minimized tissue damage

Pain Medicine - Study examined the nature of chest pain

Percutaneous Coronary Intervention - Bivalirudin treatment reduces recovery area stay after PCI

Personnel - Fred Miller named manager of sports marketing by weight loss supplement company

Personnel - Mark Stautberg named to board of directors of device company

Personnel - Medical device company appoints Tom Lindsey director of U.S. sales, marketing

Physiology - Coronary smooth muscle contraction studied, role of Mg2+ revealed

Prions - Reports add new data to prions research

Product Licensing - Biopharma company gains access to protein expression technology

Proteomics - Alpha-appendage hub analyzed, role during vesicle endocytosis clarified

Proteomics - PITX2 and MEF2A may have coordinate control in the oral epithelium

Proteomics - ZNF322 protein is a member of the zinc-finger transcription factor family

Reactive Oxygen Species - Distinct Ca2+ levels may determine mode, amount of cytochrome c release

Resveratrol - Toxicity from resveratrol seen only at the highest dose tested

Statins - Statin therapy was associated with lower levels of creatine kinase

Stents - Angiographic success rate was 97.5% in study of stent implants in small arteries

Stress - Increased cortisol activity was associated with less recent stress exposure

Stroke - A new notch in the Stroke Belt: Blacks in the South are most likely to die

Stroke - Migraine-sparked vision loss may increase stroke risk in women

Stroke - New competency guidelines for carotid stenting include virtual reality training

Stroke - Studies add new findings to stroke body of knowledge

Surgical Technology - Cutting balloon angioplasty useful for resistant venous anastomotic stenoses

Tobacco Use - Colorado Democrats introduce competing plan for tobacco tax

Tobacco Use - Iowa Governor announces cigarette tax proposal

Transplant Medicine - Implant processor signs agreement with Southeast Tissue Alliance

Vascular Disease - EGR1 is a target for AhR agonists in lung epithelial cells

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